ICS 2020 Scientific Podium Short Oral Session S24

Speakers
	On-Demand
L Lori A Birder ICS Chair G Georgi Petkov ICS Chair

#366 Is soluble VEGFR1 a putative biomarker and therapeutic target for BPS/IC?

Presenter: Ana Charrua

Ribeiro-Oliveira R¹, Mendes P², Manso M³, Pinto R², Cruz F², Charrua A¹
1. I3S and FMUP, 2. FMUP, I3S, CHSJ, 3. CHSJ
Painful Bladder Syndrome/Interstitial Cystitis (IC), Female, Basic Science

#367 PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA AGONIST AS A NOVEL TREATMENT FOR INTERSTITIAL CYSTITIS: A RAT MODEL

Presenter: Craig Comiter

Comiter C¹, Dobberfuhl A¹, Mahal A²
1. Stanford University, 2. University of Nebraska
Painful Bladder Syndrome/Interstitial Cystitis (IC), Voiding Dysfunction , Pain, Pelvic/Perineal, Animal Study

#368 Effects of a soluble guanylate cyclase activator, BAY 60-2770, on neurogenic lower urinary tract dysfunction in mice with spinal cord injury

Presenter: Daisuke Gotoh

Gotoh D¹, Saito T¹, Kurobe M¹, Igarashi T¹, Singh N¹, Miyake M², Torimoto K², Fujimoto K², Yoshimura N¹
1. University of Pittsburgh, 2. Nara Medical University
Animal Study, Detrusor Overactivity, Pharmacology, Physiology, Spinal Cord Injury

#369 NERVE GROWTH FACTOR PRECURSOR (PRONGF) EXERTS DIFFERENT BIOLOGICAL ACTIONS ON UROTHELIAL AND SMOOTH MUSCLE CELLS OF RODENTS BLADDERS.

Presenter: Lysanne Campeau

Mossa A¹, Cammisotto P², Campeau L³
1. McGill University, 2. Lady Davis Institute, 3. Jewish General Hospital, McGill University
Basic Science, Cell Culture, Molecular Biology, Pathophysiology, Neuropathies: Peripheral

#370 Inhibiting miR-21-5p alleviates bladder fibrosis and detrusor overactivity in spinal cord injured rats

Presenter: Zhenhua Shang

Shang Z¹, Ou T¹
1. Xuanwu Hospital Capital Medical University
Spinal Cord Injury, Animal Study, Detrusor Overactivity, Basic Science

#371 Sex differences in bladder wall fibrosis and compliance in spinal cord transected mice—role of angiotensin signalling

Presenter: Irina Zabbarova

Zabbarova I¹, Ikeda Y¹, Kozlowski M¹, Birder L¹, Fry C², Kanai A¹
1. University of Pittsburgh, 2. University of Bristol
Spinal Cord Injury, Basic Science, Animal Study

#372 Losartan prevents bladder fibrosis and protects renal function in rats with neurogenic bladder

Presenter: Jian Guo Wen

Wen J¹, He Y¹, Pu Q¹, Wen Y¹, Zhai R¹, Ma Y¹, Liu E¹, Xing D¹, Ji F¹, Yang X¹
1. Pediatric Urodynamic Centre, Department of Urology, the First Affiliated Hospital of Zhengzhou University, China
Animal Study, Underactive Bladder, Neuropathies: Central

#373 Urothelial lysosomal dysfunction causes bladder hyperactivity and inflammation

Presenter: Jonathan Beckel

Rodriguez R¹, Phipps S¹, Obidike C¹, Daugherty S¹, Beckel J¹
1. University of Pittsburgh, PA USA
Painful Bladder Syndrome/Interstitial Cystitis (IC), Molecular Biology, Urgency/Frequency, Voiding Dysfunction , Overactive Bladder

#374 Acid-sensing ion channel 3 (ASIC3) inhibitor increases functional bladder capacity with or without acidic irritation of lower urinary tract in mice when administering intraperitoneally but not intravesically

Presenter: Mitsuharu Yoshiyama

Yoshiyama M¹, Kobayashi H², Araki I³, Takeda M⁴
1. Shintotsuka Hospital, 2. Kobayashi Urology Clinic, 3. Koka Office of Public Health and Welfare, 4. University of Yamanashi
Basic Science, Animal Study, Painful Bladder Syndrome/Interstitial Cystitis (IC)

#375 Mast cell tryptase causes lower urinary tract dysfunction associated with chronic ischemia

Presenter: Hidenori Akaihata

Akaihata H¹, Yoshida Y¹, Imai H¹, Meguro S¹, Honda R¹, Matsuoka K¹, Hoshi S¹, Hata J¹, Sato Y¹, Kataoka M¹, Ogawa S¹, Haga N¹, Kojima Y¹
1. Fukushima Medical University
Animal Study, Overactive Bladder, Prevention

#376 Long-lasting bladder hypersensitivity with frequent urination induced by intravesical application of of hydrogen peroxide in rats with pelvic venous congestion

Presenter: Takahisa Suzuki

Suzuki T¹, Mizoguchi S², Kurobe M², Saito T², Takaoka E², Kishida T³, Yao M⁴, Yoshimura N²
1. University of Pittsburgh, Kanagawa Cancer Center, 2. University of Pittsburgh, 3. Kanagawa Cancer Center, 4. Yokohama City University
Animal Study, Painful Bladder Syndrome/Interstitial Cystitis (IC), Urgency/Frequency, Basic Science

#377 A pilot animal model to identify the intravesical bladder irritant cystometric dose response threshold for six common environmental exposures associated with overactive and painful bladder dysfunction in humans with IC/BPS

Presenter: Chen Shenhar

Shenhar C¹, Dobberfuhl A²
1. Rabin Medical Center, Div. of Urology, 2. Stanford University, Dept. of Urology
Animal Study, Basic Science, Painful Bladder Syndrome/Interstitial Cystitis (IC)

Content Visitors (staff only)

Sensory Function and Fibrosis

Scientific Podium Short Oral Session S24

Session Schedule

Sensory Function and Fibrosis

Scientific Podium Short Oral Session S24

Session Schedule

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