Incidence of Urinary Tract Infection Post Video-Urodynamics: A Prospective Audit of 2627 Patients 2014-2023.

Gill S1, Segui E2, Nobrega R1

Research Type

Clinical

Abstract Category

Urodynamics

Abstract 728
Open Discussion ePosters
Scientific Open Discussion Session 108
Friday 25th October 2024
13:10 - 13:15 (ePoster Station 1)
Exhibition Hall
Urodynamics Techniques Infection, Urinary Tract Prospective Study
1. Neuro-Urology. London Spinal Cord Injury Centre, Royal National Orthopaedic Hospital UK, 2. Neuro-Urology, London Spinal Cord Injury Centre, Royal National Orthopaedic Hospital UK
Presenter
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Poster

Abstract

Hypothesis / aims of study
Video-urodynamic study (VCMG) is the gold standard investigation for patients with bladder dysfunction.  However, it has a risk of urinary tract infection (UTI). Studies report that the incidence of UTI post-VCMG in the general population is between 1-30% [1]. In patients with spinal cord injury, it has been reported as 8% [2]. Patients with a neuropathic bladder have complex urological needs and a higher risk of UTI.
The use of prophylactic antibiotics is controversial with no definitive recommendations for its use with VCMG [3].
The objectives of this study was to determine an overall rate of UTI that could be attributable to the VCMG study; to report the evolution of UTI rates over 9 years by compared the results of our previous audit from 2017 to 2023; to evaluate the risk of UTI post-VCMG according to bladder management.
Study design, materials and methods
A prospective audit of the incidence of UTI post VCMG was conducted over 9 years, from 2014 to August 2023. Patients were divided according to their bladder management i.e. intermittent self-catheterisation (ISC), suprapubic catheter (SPC), voids, sheath only, strain voiding, pads only and indwelling urethral catheter (IDUC). 

A UTI was defined as being symptomatic and requiring antibiotic treatment within 48 hours post VCMG. 
All patients had a dipstick urinalysis pre-VCMG. Patients with a symptomatic UTI the VCMG was not performed. If the patient was asymptomatic the VCMG was conducted irrespective of the urinalysis result except for patients who void who were rebooked post treatment. All positive urinalysis to nitrites had a urine culture performed. One week post VCMG the patients were contacted and asked if they developed a UTI within 48 hours after their VCMG study according to the definition i.e. symptomatic requiring antibiotics.
Results
Number of VCMGs performed from 2014-2017 was 822. From 2014-2023 was 2627.
The overall incidence of UTI post-VCMG in 2017 was 4.44% and this has decreased to 3% in 2023. 
The highest incidence of UTI post VCMG was in the sheath drainage only (18.18% in 2017 and 19% in 2023) and in the strain voiding group 25% in 2017. This reduced to 5% in 2023. However, these low number groups would make them statistically not significant. 
The IDUC group showed a 0% incidence of UTI (66 patients) in 2017, but a slight increase in 2023 with 10 patients (3%). This patient group was predominately inpatients and a silver-coated anti-infective catheter (reduces CAUTI by 47% [5]). The patients with ISC, SPC, and voids UTI rates have reduced.
Interpretation of results
Our centre’s overall UTI incidence is one of the lowest found in the literature and demonstrates that prophylactic antibiotics are not needed unless other risk factors (immune compromised). 

We postulate that our low UTI rates compared to the published literature are for the follow reasons:
-	Highly experienced staff performing VCMG
-	Unique single centre doing a high number of VCMG
-	Protocoled procedure ‘always doing the same’
o	Patient informed verbal consent based on own UTI risk data
o	History of UTIs.
o	Dipstick urine pre-test.
o	Nitrites +ve in people who void. Treat and re-book.
Concluding message
Patient safety is the most important outcome. Performing audits, analysing and disseminating results year on year demonstrates patient safety, safe practice and contributes to informed patient consent
Figure 1 UTI rates post VCMG comparing 2014 to 2023
References
  1. Gurbuz et al 2003
  2. Sung-II et al 2016
  3. Foon, Toozs-Hobson and Latthe 2012
Disclosures
Funding none Clinical Trial No Subjects Human Ethics not Req'd Audit of practice Helsinki Yes Informed Consent Yes
18/04/2025 06:23:56