Performing gender affirmation procedures has become increasingly common. Although many transgender patients do not choose to undergo the surgical transition process, surgery remains an option, however not all patients have enough tissue to build the neovagina, so the use of a graft is necessary, such is the case of tilapia xenografts.

A descriptive and observational study was carried out, evaluating a patient treated and post-vaginoplasty surgery in the period from April 2023 to December 2023. The patient had any of the following indications for performing vaginoplasty with tilapia xenograft; non-webbed scrotum, smaller foreskin 6cm, so it was necessary to implement tilapia fish skin as a graft.

An evaluation of the evolution was carried out in a post-operative patient with a tilapia xenograft procedure, the patient with close follow-up, with daily dilations, in addition to tissue integration care, hyperbaric oxygen sessions. A biopsy and vaginoscopy were performed with adequate integration of the and biopsy with the presence of epithelialization of the tilapia xenograft.

Vaginoplasty with tilapia skin xenograft presents this surgical alternative for the development of an anatomofunctional neovagina, with tissue similar to that of the vaginal mucosa, low cost and low morbidity.

Torres ATS, Lopes BB, Silva AM, Dias MTPM, Bruno ZV, Nunes A, et al. Neovaginoplasty with tilapia fish skin: a series of eleven cases. International Urogynecology Journal [Internet]. 21 de marzo de 2022;33(8):2185-93. Disponible en: https://doi.org/10.1007/s00192-022-05150-4
Teófilo CR, Peixoto RAC, Eleutério RMN, Lima EM, De Moraes Filho MO, Bezerra LRPS, et al. Neovaginoplasty With Nile Tilapia Skin: Cytological and Microbiota Evaluation. Journal Of Lower Genital Tract Disease [Internet]. 17 de mayo de 2023;27(3):275-9.
Verde MEQL, Ferreira-Júnior AEC, De Barros Silva PG, De Castro Miguel E, Mathor MB, Lima-Júnior EM, et al. Nile tilapia skin (Oreochromis niloticus) for burn treatment: ultrastructural analysis and quantitative assessment of collagen. Acta Histochemica [Internet]. 1 de septiembre de 2021;123(6):151762.

Continence 12S (2024) 101635
DOI: 10.1016/j.cont.2024.101635