Robotic upper urinary tract reconstruction for ureteral stricture

Bourillon A1, Freton L1, Verhoest G1, Hascoet J1, Richard C1, Haudebert C1, El-Akri M1, Mathieu R1, Zhao L2, Bensalah K1, Peyronnet B1

Research Type

Clinical

Abstract Category

Anatomy / Biomechanics

Abstract 690
Open Discussion ePosters
Scientific Open Discussion Session 36
Friday 29th September 2023
15:50 - 15:55 (ePoster Station 5)
Exhibit Hall
Retrospective Study Robotic-assisted genitourinary reconstruction Surgery
1. CHU Rennes, 2. NYU Langone Health
Presenter
Links

Poster

Abstract

Hypothesis / aims of study
Ureteral strictures are mainly iatrogenic, due to abdominal surgery or traumatic ureteroscopy. Historically, open ureteral reimplantation, ileal ureter and autotransplantation were the most commonly used techniques to repair ureteral injuries. The rise of robotic surgery may have facilitated those procedures but has also been accompanied by the emergence of new upper urinary tract reconstruction techniques such as buccal mucosa graft ureteroplasty or side to side reimplantation. The aim of this study was to report the outcomes of an initial single –center experience of robotic upper urinary tract reconstruction (UUTRR) for ureteral strictures.
Study design, materials and methods
The charts of all the patients who underwent UUTRR for ureteral strictures at a single academic center between 2015 and 2022 were retrospectively reviewed. UUTRR for ureteropelvic junction obstruction, open reconstructions and ureteroileal strictures were excluded. All the remaining patients were included for analysis. The primary outcome was the absence of stricture recurrence at last follow-up defined as the need for drainage and/or surgical treatment and/or symptomatic hydronephrosis.
Results
Twenty-seven patients were included. Patients characteristics are summarized in table 1 : most of them were women (2/3), most stenosis were as expected iatrogenic, mainly due to previous abdominal surgery, and half of them were located in the pelvic portion of the ureter. Median follow-up was 10 months, with 1 patient lost to follow-up.
The surgical technique was buccal mucosa graft ureteroplasty in five cases (18.5%), Boari flap in five cases (18.5%), psoas hitch in eight cases (26%), excision and primary anastomosis in one case (3.7%) and ureterolysis + intraperitonization in one case (3.7%). Perioperative results are summarized in table 2 : mean operative time around 200 minutes, mean hospital discharge at day 3, and  mean blood losses around 80 mL. We also reported several characteristics of interest such as ureteral rest, green firefly use, and perioperative ureteroscopy. Regarding postoperative complications, eight patients had one (29.6%), but only one major one (i.e. Clavien grade 3 or higher 3.7%). After a median follow-up of 10 months, the success rate according to the primary outcome was 85.2%.
Interpretation of results
The only two predictive factors significantly associated with failure were a history of previous radiotherapy (failure risk 66.7% vs. 8.3%; p=0.02) and stricture length (OR=2.4; p=0.009).
Concluding message
Robotic upper urinary reconstruction for ureteral stricture is feasible with various techniques, either reproducing some old techniques or directly developed in robotic surgery. Preliminary reports are encouraging with low morbidity and recurrence rate. Patients who underwent radiotherapy and/or with extended ureteral strictures might have a higher risk of recurrence.
Figure 1
Figure 2
Disclosures
Funding None Clinical Trial No Subjects Human Ethics Committee Comité du CHU de Rennes Helsinki Yes Informed Consent No
28/04/2025 14:29:44