Should After-Contractions During Urodynamics Be Considered Pathognomonic for Overactive Bladder Syndrome?

Boualbanat M1, Behbehani B2, Salem S3, Alenezi A1, Alyousef R4, Al-Terki A4, Al-Shaiji T5

Research Type

Clinical

Abstract Category

Urodynamics

Abstract 607
Open Discussion ePosters
Scientific Open Discussion Session 33
Friday 29th September 2023
12:50 - 12:55 (ePoster Station 2)
Exhibit Hall
Detrusor Overactivity Retrospective Study Urodynamics Equipment Urodynamics Techniques
1. Kuwait Urology Board, Kuwait institute for medical specialization, Kuwait., 2. Intern,Kuwait institute for medical specialization, Kuwait, 3. Urology department, faculty of medicine, Menoufia university, Egypt., 4. Urology Unit, Department of surgery, Al-Amiri Hospital, Kuwait., 5. Urology Unit, Department of Surgery, Jaber Al-Ahmad Hospital, Kuwait.
Presenter
Links

Poster

Abstract

Hypothesis / aims of study
Detrusor after contraction (AC) is defined as an increase in Pdet after cessation of voiding detrusor contraction in the absence of urinary flow when bladder is nearly empty.(1) It is thought to be an ill-defined urodynamic finding, and thus the clinical and its symptomatic significance has also been vague. (2)
AC has been linked to be associated with detrusor overactivity, bladder outlet obstruction, detrusor sphincter dyssynergia or, otherwise a urodynamically normal bladder with AC being a normal physiological finding. Therefore, there is an  absence of a standardized definition, poor understanding of the pathophysiology and unclear clinical relevance. In this study, we aim to analyse the association of AC with other pathologies and its clinical impact and to establish that AC during urodynamics are pathognomonic for overactive bladder (OAB).
Study design, materials and methods
This is a retrospective cohort study.
We retrospectively analyzed 327 patients, by going through the urodynamics records of male and female patients presenting with lower urinary tract symptoms of mixed in nature in four different centers.The patients were heterogenous in diagnosis ranging from bladder outlet obstruction, true and pseudo DSD, Overactive bladder and urinary  incontinence diagnosed by urodynamics.Patients were divided to either AC without detrusor overactivity  and patients with both detrusor overactivity and detrusor AC.
Results
out of 327 patients, 230 (70.3%) patients found to have detrusor AC with different severity in which 165  (71.2%) patients were found to have detrusor AC with detrusor overactivity and 67 (29.7%) patients were found to have only detrusor AC with trivial post voiding residual
The percentage of patients showing this finding was different according to the main complaint.
In patients with urinary retention it was 5 out of 10 (50%), in patients with predominantly failure to empty symptoms, it was 16 out of 31 (51%), in patients with  LUTS of mixed in nature, it was 81 out of 112 (72%) and 125 out of 142 (88%) in patients with failure to store LUTS
Interestingly, from a clinical point of view, we found  48  patients out of 67 (71.5%) in the AC only group to report classic complaints of severe pain and pressure at the end of voiding, incomplete emptying and the need to have a second voiding.
Interpretation of results
We report the findings of aftercontractions and characters of patients indicating that detrusor after contractions during urodynamic can be considered pathognomonic for overactive bladder according to our study cohort and results. Therefore, it can be an eye opener for more researches to delineate its clinical significance.
Concluding message
We found AC during urodynamics to be common either alone or in combination with detrusor overactivity in a large cohort of patients with failure to store LUTS. Furthermore, Large percentage of patients presenting with the triadic symptoms of severe pain and pressure at the end of voiding, incomplete emptying and the need to have a second voiding were found to have AC only in the presence of trivial post voiding residual that could make it a classic presentation for the presence of AC.  Further studies are warranted in order to delineate the clinical significance of our findings.
References
  1. Detrusor afterContraction - Is it Pathological Shivalingaiah M , Nischith D Souza , Ninad Tamboli https://www.aijournals.com/index.php/ajmr/article/download/849/629/
  2. Detrusor after contractions in men with lower urinary tract symptoms: Myth or reality? https://www.sciencedirect.com/science/article/pii/S2090598X13000843
Disclosures
Funding None Clinical Trial No Subjects None
25/04/2025 10:37:39