Introduction: The management of recurrent acute prostatitis is a challenge for healthcare. 2 to 10% of men will present acute prostatitis throughout their lives.
Identified in approximately 2 to 16.5% of prostate biopsies, by needle. It is believed that about 50% of men with a high-grade PIN on biopsy, will present a carcinoma on subsequent biopsies performed within the first 2 years of follow-up (follow-up is recommended every 3 to 6 months for the first two years and every year thereafter) [1].

Objective: To identify the factors associated with the cure, stability or worsening of acute prostatitis over 10 years of follow-up in a standard Health Area.

Material and method: Prospective study of 296 men over 18 years of age treated for acute prostatitis from 01/01/2012 to 10/01/2022.

Groups according to the evolution in health-related quality of life (prostatitis) measured with SF-36. G1 (improvement, n=216): patients with acute prostatitis who have improved, G2 (remain the same, n=51): patients with acute prostatitis who remain the same, with the same complaints. G3 (worsening, n=15). Fourteen deaths from other causes were excluded from the analysis.

Variables: Age, year of admission, days of hospital stay, hospital medical specialty, urine culture results, concomitant diseases, concomitant treatments, toxic habits (smoking, alcoholism), surgical history, allergies. Descriptive statistics and multivariate logistic regression analysis. Statistical significance for p<0.05.

Mean age 61.68 years, SD 12.27 (24-91), without differences (p=0.2285). Income: year according to improvement/stability/worsening=2012:17/04/00; 2013:05/26/03; 2014:25/05/03; 2015:09/06/03; 2016:00/22/00; 2017:03/20/00; 2018:06/13/00, 2019:07/23/00; 2020:01/14/00; 2021:39/06/00; 2022:08/06/06. Mean hospital stay was 4.92 SD 0.68 (1-71) without differences. Multivariate analysis: there was more healing at an older age, years 2016, 2017, less hyperlipidemia, hypertension, urinary tract complications. Prostatitis symptoms remained stable in smokers, with diabetes and hypertension, and urine and semen cultures positive for Enterococcus. Acute prostatitis worsened with positive cultures for E coli, hyperlipidemia, smoking, urinary tract complications, renal failure, in 2013 and 2014.

In older age, less hyperlipidemia, hypertension, urinary tract complications related with prostatitis symptoms remained stable in smokers, with diabetes and hypertension, and urine and semen cultures positive for Enterococcus. Acute prostatitis worsened with positive cultures hyperlipidemia, smoking, urinary tract complications, renal failure, in 2013 and 2014.

Acute prostatitis has a worse prognosis in patients with smoking, positive cultures for Escherichia coli, urinary tract complications, and renal failure. They improve correlated with older patients. They remain stable in patients with diabetics, hypertensive patients, and with positive findings cultures for Enterococcus.

Montironi, R., et al., Morphological identification of the pattern of prostatic intraepithelial neoplasia and their importance. . J Clin Pathol 2000. 53: p. 655- 665.