INTRODUCTION: HPV is considered a sexually transmitted disease (STD), but often the exact origin cannot be determined. Different types of human papillomavirus (HPV) cause different infections, such as visible and less visible genital warts on the cervix (cervix), vagina, vulva, urethra, penis, and anus, as well as warts. common skin.
Genital warts grow rapidly and sometimes cause burning pain.
Some types of HPV infection increase the risk of developing cancer of the cervix, vagina, vulva, penis, anus, and throat.
Visible warts can be identified based on their appearance, while the least visible warts should be scanned for the cervix and anus (1).


OBJECTIVES: To determine the impact of the detection of Human Papillomavirus (HPV) as an 
etiopathogenic factor of female urethral syndrome.

MATERIAL AND METHOD: Sample of 888 women investigated by recurrent urinary tract infections (RUTI), in 41 women urethral virus research is carried out. 
Initial symptoms (IS): 1: RUTI; 2: isolated urethral pain; 3: other / various (urinary incontinence (UI), microhematuria, perineal paresthesias, micturition difficulty). Groups according to IS: GA: 2 (n = 22), GB: 3 (n = 4), GC: 1&2 (n = 8), GD: 2&3 (n = 2), GE: 1&2&3 (n = 5).

Variables: Age, follow-up time, relationship with coitus, treatment received, secondary diagnoses (DDSS: none=1, diabetes mellitus=2, overactive bladder=3, LUTS=4, 
arterial hypertension=5, anxiety=6, depression=6, smoking=7, neurogenic bladder=8), more frequent serotypes. Descriptive statistics, ANOVA analysis, Student's t test, Fisher's exact test, p <0.05 was considered significant.

Table 1. Represent the groups according IS and the varibles age, follow time, relationship with coitus and secondary diagnosis as results; younger patients are in GA and older in GD and GE. More frequent: no other secondary diagnosis (DDSS) (60.97%), smoking (19.51%) and overactive bladder (9.75%).

Most of the scientific texts assure that the virus of the human papyloma is of sexual transmission (2,3), however it cannot be demonstrated in many patients. It is a health and social problem. On the other hand, the diagnosis is influenced by the fact that the sample collection is invasive (4) and that the state of replication of the virus may be low and its determination difficult. Therefore, it is important to show that the relationship with intercourse is not always evident. Diagnosing human papillomavirus in women with urethral syndrome can be determined for better management and compression of symptoms.

Viral urethritis due to HPV is a mandatory etiology to investigate in female urethral syndrome. The findings of the present study demonstrate that traditional STD concepts have to be reviewed in this entity for proper urological management.

Maria-Luisa Mateos-Lindemann, Sonia Perez-Castro, Maria-Teresa Perez-Gracia, Manuel Rodriguez-Iglesias. Diagnostico microbiologico de la infección por el virus del papiloma humano. En Procedimientos en Microbiologia Clinica. SEIMC. ISBN 978-84-608-7617-5. Edits Emilia Cercenado-Mansilla, Rafael Canton-Moreno. Madrid 2016.
E Peyri-Rey. El urólogo ante la infección del virus del papiloma humano. Act Urol Esp 2010, (34 (1): 10-11.
Scheede P, Munch P, Wagners J, Meyer T, Stockfleth E, Hofstetter A. Flourescence urethroscopy following instillation of 5-aminolevulinic acid: a new procedure for detecting clinical and subclinical HVP lesions of the urethra. J Eur Acad Dermatol Venerol. 2001;15(2):121-5.