Study design, materials and methods
This is a cross-sectional study which took place from October 1 to 31, 2019, using a convenience sample of 62 women diagnosed with obstetric fistulas. Data were obtained from patients’ registers from outpatient consultations, emergency department as well as obstetric records, and any other hospital registers. These documents made possible to obtain necessary information on the women from their admission to the various centers of provenance until the day of the campaign. We used the interviews to supplement socio-demographic and clinical data. The physical examination included gynecological and urological assessments(2). Fistula types were determined using Kees Waldjik classification (1). Statistical analysis: Data were recorded using Microsoft Excel 2013 software, and analyzed with SPSS v.22 (Chicago, IL, USA). Continuous data were summarized using means and standard deviations whilst categorical data were presented as proportions (%) by means of tables or figures. Student’s t-test was performed to assess differences between two means. Either Chi-square test with and without trend or Fischer’s exact test was used to test the degree of association of categorical variables. The factors associated with the recurrence of obstetric fistulas were obtained using logistic regression models. Unadjusted odds ratios (ORs) were initially calculated to screen for inclusion in multivariate models while multivariate ORs (95% CI) were computed after adjusting for confounding univariate factors with a p-value <0.05 considered as significant.
Results
The mean age of the patients was 31.0 ± 7.4 years (range 20-34 years). The majority of patients came from areas located far than 60 km (61.3%) in average while 25.8% of women were residing in areas located at a distance ≤30 km. The majority of participants (48.4%) were multiparous. Labor duration exceeded 64 hours for 64.5% of women. The majority of fistulas (45.2%) were of type 1. followed by type IIBb(42%). About less than 64.5% of the patients had fistulas of less than 2 cm. The most common location of fistula was trigonal (35.5%) followed by pericervical (32%) . Age ≥35 years (p = 0.012), FVV >2 Cm of dimension (p = 0.001), presence of vaginal septum (p = 0.007) and fibrosis (p = 0.008) were respectively 3.5-fold, 3-fold, 4-fold and 4.6-fold as likely to be associated with the recurrence of obstetric fistulas, leading to multiple surgical repairs. Other risk factors included labor duration >8h (p<0.01), hysterectomia (p = 0.007), and type III fistula (p = 0.004).
Interpretation of results
Recurrence of obstetric fistulas leading to multiple surgical repairs were found to occur in older women who developed type III fistulas, whose labor period was prolonged. Fibrosis developed post-surgery was also a major risk factor for subsequent surgical repairs. Hysterectomy was also seen to be frequently associated with fistulas with complicated initial repairs, hence leading to subsequent surgical procedures.