A total of 602 women were included in this study. One hundred (16.6%) women were found to have DU, and 60 (10%) women were found to have BOO. The highest rate (39%, 7/18) of DU was in the age of more than 81 year-old, and the highest rate (17%, 8/47) of BOO was found in the age between 31 and 40 year-old.
ANOVA analysis revealed that women in the DU group were older (60.6±13.4 vs. 53.2±14.0 years, p=0.002), and had higher parity (3.1±1.6 vs. 2.4±1.8, p=0.02), lower PdetQmax (11.9±5.7 vs. 62.5±40.7 cmH2O, p<0.001), lower maximal urethral closure pressure (MUCP, 70±42 vs. 93±42 cmH2O, p<0.001) and lower functional profile length (3.0±1.3 vs. 3.5±1.3 cm, p=0.037), compared with the BOO group. After adjusting with age, the coefficient of DU (coefficient = -13.2 cmH2O, p=0.04) remained significant for predicting MUCP, compared with BOO.
Besides, women with DU were older (60.6±13.4 vs. 56.7±13.3 years, p=0.03) and had a lower Qmax (9.5±3.4 vs. 18.2±7.7 mL/s, p<0.001), lower voided volume (183±121 vs. 291±142 mL, p<0.001), higher PVR (124±117 vs. 83±84 mL, p<0.001), lower PdetQmax (11.9±5.7 vs. 58.5±30.1 cmH2O, p<0.001), compared with the non-DU/BOO group. After adjusting age, the coefficient of DU remained significant for predict voided volume (coefficient of DU = -100 mL for voided volume, p<0.001) and PVR (coefficient of DU = 39 mL for PVR, p<0.001).
Women with BOO were had a lower Qmax (8.4±2.1 vs. 18.2±7.7 mL/s, p<0.001), lower voided volume (140±118 vs. 291±142 mL, p<0.001), higher PVR (124±118 vs. 83±84 mL, p=0.006), lower strong-desire volume (224±110 vs. 289±100 mL, p=0.003), higher PdetQmax (62.5±40.7 vs. 58.5±30.1 cmH2O, p<0.001) and higher MUCP (93±42 vs. 76±35 cmH2O, p<0.001), compared with the non-DU/BOO group.
However, there were no differences in the Urgency Severity Scores, Overactive Bladder Symptoms Scores, Urogenital Distress inventory short form scores, Incontinence Impact Questionnaire, severity of bladder problems in the King’s Health Questionnaire (i.e., frequency, nocturia, urgency, urgency incontinence, stress urinary incontinence, nocturnal enuresis, intercourse incontinence, urinary tract infection, bladder pain and voiding difficulty), all domains in the King’s Health Questionnaire (i.e., general health perception, incontinence impact, role limitations, physical limitations, social limitations, personal relationships, emotion, sleep/energy and severity measures) and bladder diary variables (i.e., nocturia episodes, daytime frequency episodes, urgency episodes, incontinence episodes, total voided volume, total fluid intake and maximum voided volume per micturition) between the DU, BOO and non-DU/BOO groups.