Overall 1,079 (4.7%) women who underwent colpopexy experienced a postoperative UTI. Women undergoing a vaginal colpopexy (intra- or extraperitoneal) were more likely to develop a postoperative UTI compared to abdominal colpopexy (open or laparoscopic) (5.6% versus 3.6%, p<0.001). UTI was most frequently diagnosed in the 2nd week after surgery, 38.2%; compared to weeks 1, 3 and 4: 19.9%, 22.8%, and 19.1%, respectively.Additionally UTIs were more common in women undergoing anterior colporrhaphy (34.5% vs 25.9%, p<0.001), posterior colporrhaphy (42.3% vs 33.7%, p<0.001), and sling procedures (44.7% vs 33.7%, p<0.001). Intraoperative cystotomy was identified as the most predictive variable for a postoperative UTI (aOR=2.93; 95% CI, 1.54-5.59). On multivariate analysis, the following characteristics remained independently associated with increased risk of UTI: intraperitoneal vaginal colpopexy (aOR=1.72, 95%CI: 1.47-2.01), extraperitoneal vaginal colpopexy (aOR=1.65, 95%CI: 1.39-1.96), insulin dependent diabetes mellitus (aOR=1.65, 95% CI:1.13-2.41), chronic steroid use (aOR=1.55, 95%CI: 1.05-2.27), mid-urethral sling procedure (aOR=1.47, 95%CI: 1.29-1.67) , length of hospitalization (aOR=1.24, 95%CI: 1.15-1.29), anterior colporrhaphy (aOR=1.17, 95%CI: 1.06-1.36), posterior colporrhaphy (aOR=1.15, 95%CI: 1.03-1.33) and operation time (aOR=1.02, 95%CI: 1.01-1.03).