ICS 2015 Scientific Oral ePoster Session S24 - Biomechanics and Experimental Models

Biomechanics and Experimental Models

Speakers
	Scientific Oral ePoster Session S24
	Thursday 8th October 2015
	11:00 - 12:30
	E-Poster Area (220A)
	Lunch provided
J James Innes Gillespie ICS Chair N Naoki Yoshimura ICS Chair C Chris E Constantinou ICS Chair M Margot Damaser ICS Chair
Learning Objectives
To examine novel research findings in the field of Biomechanics and Experimental Models. To discuss methodological challenges for conducting research in the field of Biomechanics and Experimental Models. To discern the internal and external generalizability of these research results in order to implement changes in research methods or clinical practice within the participant's own setting.

Session Schedule

11:00

#300 Spreading of micromotions in juvenile rat bladder: origin points, directionality and function of gap junctions
Best Non-Clinical Presentation

Presenter: Marcus Drake

Bijos D¹, Drake M¹
1. University of Bristol, School of Physiology and Pharmacology
Basic Science, Physiology, Pharmacology
ePoster Station 1

11:00

#301 Local electrical stimulation with mesenchymal stem cells improves anatomy and functional recovery long after anal sphincter injury in a rat model.

Presenter: Massarat Zutshi

Zutshi M¹, Sun L¹, Xie Z¹, Kuang M¹, Damaser M S¹
1. Cleveland Clinic Foundation
Anal Incontinence, Animal Study, Pelvic Floor, Physiology, Anatomy
ePoster Station 2

11:00

#302 Potential improvement of pelvic organ prolapse surgery outcome using a long-term degradable scaffold with or without autologous muscle fiber fragments – a pilot study with three abdominal models in rats.

Presenter: Hanna Jangö

Jangö H¹, Gräs S¹, Christensen L², Lose G¹
1. Dept. Obstetrics and Gynecology, Herlev University Hospital, Denmark, 2. Dept. Pathology, Herlev University Hospital, Denmark
Animal Study, Basic Science, Stem Cells / Tissue Engineering, Pelvic Organ Prolapse
ePoster Station 3

11:00

#303 Cell Therapy for Neurogenic Detrusor Overactivity: Proof of Concept using Intramural Implantation of Adrenal Medullary Chromaffin Cells following Chronic Suprasacral Spinal Cord Injury

Presenter: Jillene M Brooks

Brooks J M¹, Degoski D J¹, Dolber P C², Fraser M O³
1. Institute for Medical Research/Durham Veterans Affairs Medical Center, 2. University of Texas Medical Branch at Galveston, 3. Duke University and Durham Veterans Affairs Medical Centers
Spinal Cord Injury, Stem Cells / Tissue Engineering, Basic Science, Pharmacology, Detrusor Overactivity
ePoster Station 4

11:00

#304 Human urine-derived stem cells seeded surface modified composite scaffold grafts for bladder reconstruction in a rat model

Presenter: Eun Sang Yoo

Lee J N¹, Lee H², Chun S Y², Kim B S¹, Kim H T¹, Kim T¹, Kim J H³, Troya I S³, Yoo E S¹, Kwon T G¹, Chung S K¹, Kim B W¹
1. School of Medicine, Kyungpook National University, 2. BioMedical Research Institute, Kyungpook National University Hospital, 3. College of Medicine, Yonsei University
Grafts: Synthetic, Stem Cells / Tissue Engineering, Animal Study
ePoster Station 5

11:00

#305 Keep on tripping: Also TRPM4 plays a functional role in the lower urinary tract of the rat

Presenter: Yves Deruyver

Deruyver Y¹, Uvin P¹, Pinto S¹, Everaerts W¹, Voets T¹, De Ridder D¹
1. KU Leuven
Animal Study, Basic Science, Physiology, Pharmacology
ePoster Station 7

11:00

#306 The in vivo response to implantable engineered repair materials designed for pelvic floor reconstruction

Presenter: Christopher Hillary

Roman S¹, Hillary C², Urbánkova I³, Callewaert G³, Lesage F³, Deprest J³, Chapple C⁴, MacNeil S¹
1. Kroto Research Institute, University of Sheffield, Sheffield, UK, 2. Department of Reconstructive Urology, Royal Hallamshire Hospital and University of Sheffield, Sheffield, UK, 3. KULeuven, Dept. of Development and Regeneration, Leuven, Belgium, 4. Department of Reconstructive Urology, Royal Hallamshire Hospital, Sheffield, UK
Cell Culture, Grafts: Synthetic, Stem Cells / Tissue Engineering, Stress Urinary Incontinence, Animal Study
ePoster Station 8

11:00

#307 Response of scaffold materials designed for treatment of stress urinary incontinence (SUI) and pelvic organ prolapse (POP) to distension

Presenter: Christopher Hillary

Hillary C¹, Roman S², Bullock A², Chapple C³, MacNeil S²
1. Department of Reconstructive Urology, Royal Hallamshire Hospital and University of Sheffield, Sheffield, UK, 2. Kroto Research Institute, University of Sheffield, Sheffield, UK, 3. Department of Reconstructive Urology, Royal Hallamshire Hospital, Sheffield, UK
Basic Science, Biomechanics, Cell Culture, Female, Grafts: Synthetic
ePoster Station 9

11:00

#308 Investigation of the contractile dynamics of the ex vivo urinary bladder of the pig and rabbit during filling, using spatiotemporal mapping techniques.

Presenter: Quinten King

King Q¹, Lentle R², Reynolds G², Janssen P², Hulls C², Chambers P²
1. MidCentral Health, 2. Massey University
Animal Study, Physiology, Biomechanics, Outcomes Research Methods, Pre-Clinical testing
ePoster Station 10

11:00

#309 The inhibition of non-voiding contractions due to bladder outlet obstruction by alpha1-adrenoceptor blocker: what is the mechanism underlying this effect?

Presenter: Hironobu Akino

Akino H¹, Nagase K¹, Ito H¹, Yokokawa R¹, Matsuta Y¹, Aoki Y¹, Yokoyama O¹
1. Department of Urology, University of Fukui
Animal Study, Bladder Outlet Obstruction , Basic Science
ePoster Station 11

11:00

#310 Intrathecal OnabotulinumtoxinA improves bladder function after spinal cord injury and efficiently supresses neurogenic detrusor overactivity

Presenter: Francisco Cruz

Oliveira R¹, Coelho A², Cruz F³, Cruz C¹
1. Dept. Experimental Biology, Faculty of Medicine, University of Porto; Instituto de Investigação e Inovação em Saúde, University of Porto; Instituto de Biologia Molecular e Celular, University of Porto, 2. Dept. of Renal, Urologic and Infectious Disease, Faculty of Medicine, University of Porto; Intstituto de Investigação e Inovação em Saúde, University of Porto; Instituto de Biologia Molecular e Celular, University of Porto, 3. Dept. of Urology, Hospital São João, Porto; Intstituto de Investigação e Inovação em Saúde, University of Porto; Instituto de Biologia Molecular e Celular, University of Porto
Detrusor Overactivity, Incontinence, Spinal Cord Injury, Pharmacology
ePoster Station 12

11:00

#311 Urodynamic effects of intravenous and intrathecal administration of E-series prostaglandin 1 receptor antagonist on detrusor overactivity in rats with spinal cord injury

Presenter: Naoki Wada

Wada N¹, Kadekawa K², Majima T², Shimizu T², Tyagi P², Kakizaki H³, Yoshimura N²
1. Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, Department of Renal and Urological Surgery, Asahikawa Medical University, Japan, 2. Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, 3. Department of Renal and Urological Surgery, Asahikawa Medical University, Japan
Detrusor Overactivity, Spinal Cord Injury, Pharmacology, Overactive Bladder
ePoster Station 13

11:00

#312 LONG-TERM CALORIC RESTRICTION MAY PREVENT IN VIVO LOWER URINARY TRACT DYSFUNCTION ASSOCIATED WITH AGEING IN MALE RATS

Presenter: Jun Kamei

Kamei J¹, Ito H², Aizawa N², Sugiyama R², Akiyama Y¹, Ichihara K², Fujita Y³, Ito M³, Andersson K⁴, Homma Y⁵, Igawa Y²
1. Departs of Continence Medicine and Urology,The university of Tokyo Gradual School of Medicine, 2. Department of Continence Medicine, The University of Tokyo Graduate School of Medicine, 3. Molecular Gerontology, Research Team for Mechanism of Aging, Tokyo Metropolitan Institute of Gerontology, 4. Aarhus Institute of Advanced Studies, Aarhus University, Aarhus, Denmark, 5. Department of Urology, The University of Tokyo Graduate School of Medicine
Animal Study, Gerontology, Prevention, Male, Voiding Dysfunction
ePoster Station 14

11:00

#313 A novel extracellular calcium-sensing system in pig urethral smooth muscle cells

Presenter: Shunichi Kajioka

Kajioka S¹, Hayashi M¹, Takahashi R¹, Maki T¹, Namitome R¹, Naito S²
1. Department of Urology Kyushu University, 2. Hara Sanshin Hospital
Physiology, Pharmacology, Basic Science
ePoster Station 15

11:00

#314 Finite Element Modeling comparing biomechanical efficacy of sacrocolpopexy with and without supra-cervical hysterectomy for pelvic organ prolapse

Presenter: Rajeev Ramanah

Canaguier M¹, Vega A², Jacquet E², Chambert J², Riethmuller D¹, Ramanah R¹
1. Besancon University Medical Centre, 2. University of Franche-Comte
Anatomy, Biomechanics, Imaging, Pelvic Organ Prolapse, Surgery
ePoster Station 16

11:00

#315 Differences in activation patterns of pelvic floor EMG upon stimulation of sacral roots– New insights in optimizing lead placement for sacral neuromodulation

Presenter: Stefan De Wachter

De Wachter S¹, Voorham J², Putter H³, Lycklama à Nijeholt G², Voorham - van der Zalm P²
1. University Hospital Antwerpen,Dep.of Urology, Antwerpen, Belgium, 2. Leiden University Medical Center, Dep. of Urology, Leiden, The Netherlands, 3. Leiden University Medical Center, Dep. of Medical Statistics, Leiden, The Netherlands
Neuromodulation, Overactive Bladder, Pelvic Floor
ePoster Station 17

Biomechanics and Experimental Models

Session Schedule

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