ICS 2015 Scientific Oral ePoster Session S16 - Molecular Mechanisms of Sensation

Molecular Mechanisms of Sensation

Speakers
	Scientific Oral ePoster Session S16
	Wednesday 7th October 2015
	16:00 - 17:30
	E-Poster Area (220A)
	Lunch provided
J James Innes Gillespie ICS Chair N Naoki Yoshimura ICS Chair C Chris E Constantinou ICS Chair M Matthew Oliver Fraser ICS Chair
Learning Objectives
To examine novel research findings in the field of Molecular Mechanisms of Sensation. To discuss methodological challenges for conducting research in the field of Molecular Mechanisms of Sensation. To discern the internal and external generalizability of these research results in order to implement changes in research methods or clinical practice within the participant's own setting.

Session Schedule

16:00

#225 Urothelial Dysfunction and Alterations of Sensory Protein Expressions in Bladder Mucosa in Patients with Idiopathic Detrusor Underactivity

Presenter: Yuan-Hong Jiang

Jiang Y¹, Liu H¹, Kuo H¹
1. Department of Urology, Buddhist Tzu Chi General Hospital and Tzu Chi University, Hualien, Taiwan
Gerontology, Pathophysiology, Underactive Bladder
ePoster Station 1

16:00

#226 TRPM7 contributes to intercellular junction formation in the urothelium - Possible link to the pathophysiology of interstitial cystitis

Presenter: Masaki Watanabe

Watanabe M¹, Suzuki Y², Uchida K², Miyazaki N³, Murata K³, Matsumoto S¹, Kakizaki H¹, Tominaga M²
1. Asahikawa Medical University, Asahikawa, Japan, 2. Division of Cell Signaling, Okazaki Institute for Integrative Bioscience, National Institute of Natural Sciences, Okazaki, Japan, 3. Elecron Microscopy Group, National Institute for Physiological Sciences, National Institute of Natural Sciences, Okazaki, Japan
Cell Culture, Basic Science, Physiology, Painful Bladder Syndrome/Interstitial Cystitis (IC)
ePoster Station 2

16:00

#227 Effects of Estrogen Receptor activation on Prostatic inflammation and Bladder Overactivity in a Rat Model of Chronic Nonbacterial Prostatitis

Presenter: Shinsuke Mizoguchi

Mizoguchi S¹, Mori K¹, Sato F¹, Yoshimura N², Mimata H¹
1. Department of Urology, Oita Univerity Faculty of Medicine, 2. Department of Urology University of Pittsburgh
Male, Pain, Pelvic/Perineal, Basic Science, Detrusor Overactivity
ePoster Station 3

16:00

#228 The therapeutic efficacy of human umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs) on ketamine induced cystitis

Presenter: Aram Kim

Kim A¹, Song M¹, Yu H Y², Yoon S J², Lim J², Shin D², Choo M¹
1. Asan medical center, 2. University of Ulsan College of Medicine
Painful Bladder Syndrome/Interstitial Cystitis (IC), Stem Cells / Tissue Engineering, Outcomes Research Methods
ePoster Station 4

16:00

#229 REDUCED AFFERENT SENSITIVITY IN THE RAT BILATERAL PELVIC NERVE CRUSH MODEL OF DETRUSOR UNDERACTIVITY

Presenter: Christopher Chermansky

Chermansky C¹, Kadekawa K¹, Okada H¹, Fraser M O², Tyagi P¹, Yoshimura N¹
1. Dept of Urology - University of Pittsburgh, 2. Dept of Urology - Duke University
Underactive Bladder, Animal Study, Neuropathies: Peripheral, Basic Science, Physiology
ePoster Station 5

16:00

#230 DIRECT INFLUENCE OF SYSTEMIC DESENSITIZATION BY RESINIFERATOXIN ON THE ACTIVITIES OF A-DELTA- AND C-FIBERS IN THE RAT PRIMARY MECHANOSENSITIVE AFFERENTS

Presenter: Naoki Aizawa

Aizawa N¹, Ito H¹, Sugiyama R¹, Kamei J¹, Akiyama Y¹, Ichihara K¹, Homma Y², Igawa Y¹
1. Department of Continence Medicine, The University of Tokyo Graduate School of Medicine, 2. Department of Urology, The University of Tokyo Graduate School of Medicine
Basic Science, Pharmacology, Physiology
ePoster Station 6

16:00

#231 Can H Reflex be a suitable surrogate measure of bladder afferent activity?

Presenter: Martin Slovak

Slovak M¹, Barker A², Chapple C³
1. Devices For Dignity, Sheffield Teaching Hospital NHS Foundation Trust, 2. Medical Physics & Clinical Engineering, Sheffield Teaching Hospital NHS Foundation Trust, 3. Department of urology, Sheffield Teaching Hospital NHS Foundation Trust
Physiology, Basic Science, Pathophysiology
ePoster Station 7

16:00

#232 Possible local circuits between the bladder and the major pelvic ganglion in the modulation of non-voiding activity in the rat.

Presenter: Sara Persyn

Persyn S¹, De Wachter S¹, Eastham J², Gillespie J²
1. Department of Urology, University of Antwerp, Antwerp, Belgium, 2. Uro-physiology Research Group, The Dental and Medical School, Newcastle University, Newcastle upon Tyne, England
Basic Science, Animal Study, Physiology
ePoster Station 8

16:00

#233 Heterogeneity And Complexity Of Putative Afferent Nerves In The Sub-Epithelial And Muscle Layers Of The Proximal Urethra Of The Female Rat

Presenter: Monica Eggermont

Eggermont M¹, De Wachter S¹, Eastham J², Gillespie J²
1. University of Antwerp, 2. Newcastle University
Basic Science, Female, Animal Study
ePoster Station 9

16:00

#234 The effect of intravesical liposome-based NGF antisense therapy on bladder overactivity and nociception in a rat model of cystitis induced by hydrogen peroxide.

Presenter: Tsuyoshi Majima

Majima T¹, Tyagi P², Dogishi K³, Kadekawa K⁴, Kashyap M², Wada N⁵, Takai S⁶, Shimizu T⁷, Gotoh M⁸, Chancellor M⁹, Yoshimura N²
1. University of Pittsburgh, Nagoya University Graduate School of Medicine, 2. University of Pittsburgh, 3. Graduate School of Pharmaceutical Sciences, Kyoto University,, 4. University of Pittsburgh, Southern Knights' Laboratory LLP, 5. University of Pittsburgh, Asahikawa Medical University, 6. University of PIttsburgh. Nagoya University Graduate School od Medicine, 7. University of Pittsburgh, Kochi Medical School, Kochi University, 8. Nagoya University Graduate School of Medicine, 9. William Beaumont Oakland University School of Medicine
Animal Study, Painful Bladder Syndrome/Interstitial Cystitis (IC), Basic Science, Detrusor Overactivity
ePoster Station 10

16:00

#235 BAY 58-2667, a soluble guanylyl cyclase activator, prevents cyclophosphamide induced cystitis in mice.

Presenter: Mariana Gonçalves Oliveira

Oliveira M G¹, Antunes E¹
1. Faculty of Medical Sciences, Department of Pharmacology, University of Campinas
Painful Bladder Syndrome/Interstitial Cystitis (IC), Pharmacology, Voiding Dysfunction
ePoster Station 11

16:00

#236 GAG-replenishment: protecting the urothelium from chronic damage.

Presenter: Boy Rozenberg

Rozenberg B¹, Janssen D¹, Jansen K¹, Schalken J¹, Heesakkers J¹
1. RadboudUMC, Department of Urology
Painful Bladder Syndrome/Interstitial Cystitis (IC), Basic Science, Cell Culture
ePoster Station 12

16:00

#237 The alpha1-adrenoceptor antagonist prazosin radiosensitises hypoxic prostate cancer cells

Presenter: Amanda Forbes

Forbes A¹, McDermott C¹, Anoopkumar-Dukie S², Christie D³, Chess-Williams R¹
1. Bond University, 2. Griffith University, 3. Genesis CancerCare
Pharmacology, Basic Science, Cell Culture
ePoster Station 13

16:00

#238 Neuronal distribution of P2X3 receptor and its inhibitory effect on detrusor contractility

Presenter: Vivian Cristofaro

Cristofaro V¹, Yalla S V¹, Sullivan M P¹
1. Boston VA Helathcare System, Harvard Medical School
Basic Science, Pharmacology, Physiology
ePoster Station 14

Molecular Mechanisms of Sensation

Session Schedule

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